Download PDF by W.H. Moos,M.R. Pavia,B.K. Kay,Andrew D. Ellington: Annual Reports in Combinatorial Chemistry and Molecular

By W.H. Moos,M.R. Pavia,B.K. Kay,Andrew D. Ellington

ISBN-10: 0792357221

ISBN-13: 9780792357223

ISBN-10: 9401707383

ISBN-13: 9789401707381

Combinatorial chemistry and molecular range techniques to medical inquiry and novel product R&D have exploded within the Nineties! for instance, within the coaching of drug applicants, the computerized, permutational, and combinatorial use of chemical construction blocks now permits the iteration and screening of unparalleled numbers of compounds. Drug discovery - larger, quicker, more cost-effective? certainly, extra compounds were made and screened within the Nineteen Nineties than within the final hundred years of pharmaceutical learn.
this primary quantity covers: (i) combinatorial chemistry, (ii) combinatorial biology and evolution, and (iii) informatics and comparable issues. inside every one part chapters are ready by way of specialists within the box, together with, for instance, in part I: assurance of mix swimming pools vs. parallel person compound synthesis, resolution vs. solid-phase synthesis, analytical instruments, and automation. part II highlights choice concepts and library-based evolution, phage show, peptide and nucleic acid libraries. part III covers databases and library layout, excessive through-put screening, coding ideas vs. deconvolutions, highbrow estate matters, bargains and collaborations, and successes to date.

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Annual Reports in Combinatorial Chemistry and Molecular Diversity: 1 (Annual Reports in Combinatorial Chemistry & Molecular Diversity) by W.H. Moos,M.R. Pavia,B.K. Kay,Andrew D. Ellington

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